Study reports popular Antiageing supplement has no economic effects

One widely used anti-aging supplement has no effect on aging tags such as muscle strength, peak endurance, muscle mass, fat mass and glucose tolerance in older men and women, Mayo Clinic researchers according to. The findings appear from their two-year study in the Oct. 19, 2008 issue of the New England Journal of medicine, the results are used, the faith to dispel that dehydroepiandrosterone (DHEA) sold largely anti aging supplement in health and grocery stores, age-related changes in body composition and function, to reverse as one, lead author of the study k. Sreekumaran Nair, m.d, Mayo Clinic endocrinologist says. "For almost two years, we restored the DHEA in older men and women on the normal high observed in young people, but found no positive effect on age-related changes in body composition and function," says Dr. Nair. "No positive effects on quality of life were observed." "There is no evidence, on the basis of this study, DHEA has an anti-aging effect." The double blind study involved 87 men and 57 women were followed for two years. Participants showed no change in several markers of Alterns--body composition, physical performance, insulin sensitivity or quality of life. Mayo Clinic's findings contradict some of the previous reports about DHEA. Dr. Nair says many earlier studies on shorter periods were made and no big concern enough group of topics. Mayo's study was also increased, because there is a double blind, placebo-controlled, randomized study was. DHEA was administered only people with low DHEA and testosterone levels. Dr. Nair gets DHEA use a controversial issue like Antiageing sales in the health food industry supplements drive. He advises elderly stop with DHEA, because it is unlikely that all anti aging effect to offer. DHEA as an anti-aging supplement was promoted the authors say the study, partly because high DHEA longevity in humans and non-human primates have been assigned. But studies where rodents like rodents have very low levels of DHEA are applicable to humans, the authors say. The study included testosterone on older men low doses, the low levels of testosterone. Found testosterone minimal positive impact on bone density offered the authors, and far less than that of many current accepted treatments offered. Investigators found no negative side effects though to warn the conducted only in men without prostate problems. The New England Journal of Medicine published an accompanying editorial Mayo's study, Stewart of Paul, m.d; from the University of Birmingham, Alabama, will say search after eternal youth. But in view of the findings of Mayo, he suggests DHEA should no longer as a nutritional supplement should be accepted and instead treated as regulated drug. "Quackery to would dispel much of the associated this elusive hormone appropriate regulation," writes Dr. Stewart. Mayo's study was conducted by the study team without support from the industry. The study of other authors are Robert Rizza, MD; Peter O'Brien, Ph.d.; Ketan Dhatariya, m.d.; Kevin, Ph.d.; Ajay Nehra, m.d.; Janet Vittone, m.d.; George Klee, m.d, Ph.d.; Ananda Basu, M.B.B.S.; Rita Basu, m.d.; Claudio Cobelli, Ph.d.; Gianna Toffolo, Ph.d.; Chiara Dalla man, Ph.d.; Donald Tindall, Ph.d.; LJ Melton, III, MD; Glenn Smith, Ph.d.; Sundeep Khosla, m.d.; and Michael Jensen, MD

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