Wednesday, November 17, 2010

Health risks reduce aging men through physical activity

New research suggests that exercise in aging men, the risk of developing of benign prostatic hyperplasia can reduce hyperplasia (BPH), lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Our results suggest that moderate to strong physical activity reduce the risk of benign prostatic hyperplasia (BPH) or lower urinary tract symptoms (LUTS) of less than 25% relative to a sedentary lifestyle could. Although the strength of the association with higher levels of activity exceed seems, there was a non-significant trend towards a protective effect with even mild physical activity. Adjustment for multiple disturbance variables included in the studies in this analysis underlines the independence of the protective effect of exercise on BPH/LUTS complex. The idea that physical activity and other factors can change modifiable lifestyle of risk and severity of BPH and LUTS challenges traditional etiological paradigms and the need for the development of new pathogenic models for BPH/LUTS disease implies complex. The assumption that BPH and LUTS are relatively unchanging consequences of aging driven by a combination of genetic predisposition, androgens and estrogens supported previous models. While genotype and hormones are important components, the relationship of physical activity with BPH LUTS requires taking into account the additional modulators of these processes. It is possible that physical activity prostate growth paths through influenced changes in hormone levels. We do however feel a more likely explanation is that benefits through improved cardio cardiovascular health engaged in physical activity. Pre-clinical and observational data suggest BPH and LUTS could promote cardiovascular disease. Men suffering from BPH tend components of metabolic syndrome and LUTS, have as men with heart disease. The metabolic syndrome is associated with systemic inflammation, oxidative stress and inflammation drives potentially BPH. Exercise that promotes, weight loss, improving the vascular flow normalizes the concentration of serum lipid and lipoprotein and prevent heart disease may be the lower urinary tract mitigate manifestations of systemic cardiovascular disease. In fact, BPH/LUTS often occurs complex in conjunction with erectile dysfunction (ED) is strongly associated with cardiovascular disease. It is thus possible that the BPH/LUTS is a complex and ED common etiology which share associated with cardiovascular disease. A shared heart vascular etiology for BPH/LUTS complex and ED would explain why the 2 conditions same modifiable lifestyle factors, including obesity, diabetes and hyperlipidemia are associated with. In addition, a lower risk of erectile dysfunction was associated with increased physical activity. Posted by j. Kellogg Parsons, MD European Urology 2008 Mar 11. (EPub)
Doi:10.1016/j.eururo.2008.02.019 link to original abstract: http://www.urotoday.com/41/browse_categories/bph__male_luts/physical_activity_benign_prostatic_hyperplasia_and_lower_urinary_tract_symptoms__abstract.html

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