Sunday, October 31, 2010

Accordingly new popular Antiageing supplement has no economic effects

One widely used anti-aging supplement has no effect on aging tags such as muscle strength, peak endurance, muscle mass, fat mass and glucose tolerance in older men and women, Mayo Clinic researchers according to. The findings appear from their two-year study in the Oct. 19, 2008 issue of the New England Journal of medicine, the results are used, the faith to dispel that dehydroepiandrosterone (DHEA) sold largely anti aging supplement in health and grocery stores, age-related changes in body composition and function, to reverse as one, lead author of the study k. Sreekumaran Nair, m.d, Mayo Clinic endocrinologist says. "For almost two years, we restored the DHEA in older men and women on the normal high observed in young people, but found no positive effect on age-related changes in body composition and function," says Dr. Nair. "No positive effects on quality of life were observed." "There is no evidence, on the basis of this study, DHEA has an anti-aging effect." The double blind study involved 87 men and 57 women were followed for two years. Participants showed no change in several markers of Alterns--body composition, physical performance, insulin sensitivity or quality of life. Mayo Clinic's findings contradict some of the previous reports about DHEA. Dr. Nair says many earlier studies on shorter periods were made and no big concern enough group of topics. Mayo's study was also increased, because there is a double blind, placebo-controlled, randomized study was. DHEA was administered only people with low DHEA and testosterone levels. Dr. Nair gets DHEA use a controversial issue like Antiageing sales in the health food industry supplements drive. He advises elderly stop with DHEA, because it is unlikely that all anti aging effect to offer. DHEA as an anti-aging supplement was promoted the authors say the study, partly because high DHEA longevity in humans and non-human primates have been assigned. But studies where rodents like rodents have very low levels of DHEA are applicable to humans, the authors say. The study included testosterone on older men low doses, the low levels of testosterone. Found testosterone minimal positive impact on bone density offered the authors, and far less than that of many current accepted treatments offered. Investigators found no negative side effects though to warn the conducted only in men without prostate problems. The New England Journal of Medicine published an accompanying editorial Mayo's study, Stewart of Paul, m.d; from the University of Birmingham, Alabama, will say search after eternal youth. But in view of the findings of Mayo, he suggests DHEA should no longer as a nutritional supplement should be accepted and instead treated as regulated drug. "Quackery to would dispel much of the associated this elusive hormone appropriate regulation," writes Dr. Stewart. Mayo's study was conducted by the study team without support from the industry. The study of other authors are Robert Rizza, MD; Peter O'Brien, Ph.d.; Ketan Dhatariya, m.d.; Kevin, Ph.d.; Ajay Nehra, m.d.; Janet Vittone, m.d.; George Klee, m.d, Ph.d.; Ananda Basu, M.B.B.S.; Rita Basu, m.d.; Claudio Cobelli, Ph.d.; Gianna Toffolo, Ph.d.; Chiara Dalla man, Ph.d.; Donald Tindall, Ph.d.; LJ Melton, III, MD; Glenn Smith, Ph.d.; Sundeep Khosla, m.d.; and Michael Jensen, MD

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Age-related macular degeneration (AMD), the silent disease that causes loss of sight

About 200,000 age-related macular degeneration (AMD) get diagnosed every year. Age-related macular degeneration is the leading cause of loss of vision in the adult age 60 and older. It affects the macula that section of the eye focuses on fine detail. As a result, causes AMD the sharp, central vision loss for normal daily tasks such as, for example, reading and travel is required. This disease although it both sexes are affected, it affects women more frequently than men, according to several large studies under the direction of the Wills Eye Institute in Philadelphia.

Risk factors

Age is the biggest risk factor for AMD.Abgesehen other risk factors include age:

Sex (AMD affects women more than men;)(Women live longer) SmokingObesityFamily history race (European adults are more likely to lose vision of AMD as African Americans).

The silent disease

AMD can sneak on people, because it can gradually progress and beinhaltet.Aufgrund of these factors can no pain the AMD progress, without being noticed until it's too late, and vision in both eyes cause kann.deshalb it is so important to get regular eye exams.

Early detection is the key

Early detection can slow the loss of vision.

Treatment options

Treatment options include:

Drugs,
Laser therapies
Vitamins and
Vision support the devices.

Thanks to the technology, there are many new treatments on the horizon.These include:

Anti-VEGF (Vascular Endothelial growth factor) drugs.Anti-VEGF drugs to prevent new blood vessel formation, the cause of a type of AMD, and regular injections into the Auge.Die require newer drugs work by destroying strands of messenger RNA that for the production of harmful proteins responsible require obsolete.you fewer injections.Newer drugs, including small interfering RNA.To reduce the incidence of Intravitreal injection of older drugs.

Warning signs

There are also signs the AMD zugeordnet.Wenn experience the following symptoms of vision, contact an eye care specialist:

Lines or edges, the wavy or distorted appear; diffused faces difficulties to see colors; dark or empty spaces that the center of your vision to block; difficulty reading fine print or read road signs from a moving vehicle; or difficulty to see at a distance or during the night.

Prevention

AMD can be diagnosed in a routine eye examination.

The American Academy of Ophthalmology recommends a comprehensive eye exam every one to two years for senior citizens at the age of 65, and every two to four years for adults between 40 and 65.

Your eye doctor can you also a special diagram known an Amsler grid, you take with you and use to identify early problems.

When AMD runs in your family, we recommend that you speak an ophthalmologist appropriate screening measures.

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Saturday, October 30, 2010

Cell mutations to age to apoptosis lead may according to recent bear.

A study has found that mutations in the mitochondrial DNA of obesity and lack of movement-not oxidative stress before free Radikalen--may be a key factor in the aging process of the study, published in this Friday's issue of the journal Science, University of Florida finds that promote accumulation of mitochondrial mutations, the apoptosis or programmed cell death, aging drive may be a central mechanism and may regardless of version radicals free, previously thought to cause aging. This may the cellular powerhouse that converts food into energy due to the accumulation of DNA mutations in the mitochondrial DNA. Results from the study can be more effective methods to prevent aging and underline the importance of a healthy lifestyle, Christiaan Leeuwenburgh, associate professor at the Department of aging and geriatric research in the College of medicine and post said study author lead. He estimated that average maximum human life from the current 70 years on more than 100 years with exercise and a proper diet could be increased. "All therapies is intended to reduce free radical production in the mitochondria, and now looks like the non-exhaustive sense make it", he said. Breeding to recognize mice with the disabilities and repair errors in the DNA replication process discovered researchers there has been no increase in oxidative stress despite increased co-investor. However, said there was a significant increase of apoptosis, Leeuwenburgh. In mammals, uncorrected errors can cause that genetic diseases, ageing or even to death, PhD student Asimina Hiona, which was much in the biochemical analysis of free radicals and apoptosis in the study said. In mutant mice the ability was impaired, so that the cells could not repair. Finding refutes the theory of aging, indicating that increases of mitochondrial mutations increase oxidative damage, which is a cause of aging believed mitochondrial "vicious circle". "Previously believed, that you, the more free more mitochondrial mutations producing radicals you go", said Leeuwenburgh. "But this is one thing, this paper shows that this is not necessarily the case." The mice used in the study both the paper and Greg Kujoth, an Assistant Scientist were of Thomas Prolla, a professor and senior investigator bred the genetics Department at the University of Wisconsin. "Accelerated aging mice can one system links to discover, improve function in aging individuals and maybe stop or prevent that some of the diseases associated with ageing," said Prolla. The researchers discovered that on average the mutant mice so long lived one third as normal mice. Only nine months old she experienced significant loss of hair, consultation, bone mass, intestinal lining and total weight, conditions the similar to those of an aging people. Unchanged, the same mice usually 30 to 32 months life. Also, no programmed cell death between mutant and control was observed mice at the age of 3 months. Time reached mice 9 months found but significant quantities of programmed cell death in the testicles, heart, thymus and other organs. Although, the mice were considered a "model" of aging, you was a chronic inflammatory component that can cause, cardiovascular disease, Alzheimer's disease and other health problems affecting, as you age individuals. Chronic inflammation is associated with increased production of free radicals produced by other sources, such as white blood cells. "As we age we will become stiff and have pain and processes, the inflammation," said Leeuwenburgh. He added that inflammation can be prevented by an ideal body weight by caloric restriction and movement. If a healthy human lifestyle, then the stem cells therapy, nano-technology practice and special exercise and dietary interventions are even better, he said.

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Friday, October 29, 2010

Blood test to identify Alzheimer's risk on the horizon

A simple blood test to detect whether a person could develop Alzheimer's disease is in sight and could eventually help, scientists in your quest toward reverse Alzheimer's onset in which to develop the debilitating neurological disease probably.? Based on a study that older people has started 20 years ago with a population in northern Manhattan at risk or in various stages of development of Alzheimer's disease'se, a Columbia University Medical Center Research Group provided breakthrough results, the change treated the manner of Alzheimer's or to prevent it could one day. These results indicate that by looking at the blood doctors may be located, a person, the predisposition to the development of dementia-inducing disease, a person deprived your memory to recognize and ability essential tasks. Results online in the proceedings of the National Academy of Sciences during the week of September 8, 2008 presented suggest that a particular persons with increased peptide in blood plasma, amyloid-beta-42 (Ass42), increased risk are for the development of Alzheimer's disease, decline of Ass42 into the blood stream can play, the Division of tasks and "Traffic jam" Ass42 in the brain the in of people with Alzheimer's disease of the brain. "So far Ass42 levels most reliably JC, measured in the liquor that is more difficult to collect blood," said Nicole Schupf, Ph.d, p.h., Associate Professor of clinical epidemiology at Columbia University Medical Center and lead author of the paper. "Blood draws with relative ease to be made and more often than spinal taps, typically the way and way liquor is JC." In this study, the researchers found that levels of Ass42 displayed are to increase before the onset of Alzheimer's disease and the decline shortly after the beginning of dementia. Researchers suspect that Ass42 can get into the brain that could make up for the decline in levels post dementia. The principal investigator of the northern Manhattan study Richard Mayeux, m.d, m.s., Professor of Neurology, psychiatry, and epidemiology and Co-Director of the Taub, the statement compares to something similar, that is seen Institute of research on Alzheimer's disease and the aging brain at CUMC, in heart attack patients have collected usually blood lipid levels in their blood stream before a heart attack can reduce but post heart attack lipid levels. With more specific antibodies developed by Ravetch laboratory at the Rockefeller University researchers have in promoting the most harmful form of amyloid composite, Protofibrillar form from ACE, according to Dr. Mayeux, who is the lead author of this paper. While the cognitive impairments of Alzheimer's disease in the entire course of the disease can be monitored, doctors have not a reliable way, had to monitor the pathological progression of Alzheimer's disease. Knowing how ACE levels in the blood measure reliably clinicians with a tool could provide that much earlier predicts the onset of Alzheimer's disease. Of early detection course would be an important step in combating Alzheimer's disease, researchers said. This research is supported by a program project grant from the national institutes of Health National Institute of aging. Other authors on the paper by the Columbia University Medical Center include Ming x. Tang, Ph.d, Jennifer manly, Ph.d, and Howard Andrews, Ph.d. The Department of Immunology at New York State Institute for basic research in developmental disabilities, Staten Iceland, New York, also contributed to this research. A picture of a brain tissue coated with amyloid plaque is a copy PNAS paper is available on request. The numb Institute for Alzheimer's disease and the aging brain at Columbia University Medical Center is a multidisciplinary group, the links between researchers and clinicians reveal the causes of Alzheimer's disease, age-related brain diseases and ways discover Parkinson's disease and other to prevent and forged to cure these diseases. Deaf neuroscientist partner with researchers at the Gertrude H. Sergievsky Center at Columbia University Medical Center, a foundation in 1977 to by focus, founded in diseases of the nervous system. The Sergievsky Center integrates traditional epidemiology with genetic analysis and clinical examination for exploring all phases of diseases of the nervous system. For more information about these centers CUMC visit: http://www.cumc.columbia.edu/dept/taub/ or
http://www.cumc.Columbia.edu/Dept/sergievsky/. Columbia University Medical Center offers international leadership in basic, preclinical and clinical research in medical and health sciences education and patient care. The medical centre train future leaders and includes work involved many doctors, scientists, public health professionals, dentists and nurses at the College of physicians and surgeons, the Mailman School of public health, the College of dental medicine, the school of nursing, the bio-medical departments of the Graduate School of Arts and Sciences, and allied research centres and institutions. Founded in the year 1767, Columbia's College of physicians and surgeons was the first institution of the country granting the m.d and is among the most selective medical schools in the country. Columbia University Medical Center is home to the largest medical research company in New York City and State, and one of the largest in the United States.For more information, please visit http://www.cumc.columbia.edu. About Alzheimer's disease Alzheimer's disease (AD) is a slowly progressive disease of the brain, characterized by impairment of memory and lastly by errors in the reasoning, planning, language and perception. Alzheimer's disease is the leading cause of dementia that afflicts 24 million people worldwide. The Alzheimer's disease is not a normal part of aging and is not something inevitably happens later in life.It is rarely before the age of 65 gesehen.Die probability of having Alzheimer's disease increases considerably after the age of 70 and can affect approximately 50% of people in the age of 85.

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Hyaluronic Acid Can Make You More Confident In Your Own Skin Posted By : Claudia Phillips

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May cognitive function and brain improve efficiency simple lifestyle changes.

A UCLA research study that in the June issue of the American Journal of Geriatric Psychiatry published found that people be able to improve their cognitive function and brain efficiency by you healthy simple lifestyle changes such as such as integrating memory exercises, diet, fitness and stress in your daily life may

"We have known for years that diet and exercise can help people maintain their physical health and living longer, but maintaining mental health is as important", said project manager, Gary small, m.d, Professor of Psychiatry and Biobehavioral Sciences at the Semel Institute for Neuroscience and human behavior at UCLA. "The UCLA study is the first show of the impact of memory exercises and stress reduction, along with a healthy diet and physical activity are used to improve brain and cognitive function." Researchers found that after 14 days following strategies, study healthy lifestyle participants brain metabolism decreased in the work areas that suggested an increased efficiency ? the brain to work as hard to tasks. For the two-week trial, 17 topics with normal baseline memory performance results were randomly allocated two groups: a control group made no changes behavior while a test group healthy longevity strategies for improving the physical and mental function.Details of the healthy strategies in the study are busy highlighted in small's new book, today released, called "the longevity Bible: 8 essential strategies for keeping your mind sharp and your body young" (Hyperion, New York, 2006) .Teilnehmer healthy longevity scheduled the following into your daily routine:
Stimulate to the brain, memory exercises conducted cross word puzzles and brainteasers throughout the day. Improve physical fitness, took participants daily walks to increase life expectancy and lower the risk of Alzheimer's disease found. Improve your diet, participants ate five small meals a day, the drop in blood glucose levels, on the plan prevented because glucose is the main source of energy for the brain. In addition, they ate a balanced diet full of Omega-3 fats, antioxidants and low Glycemic carbohydrates like whole grains. Participants conducted to stress to manage, daily exercises. Small notes that stress causes body cortisol, a hormone that publish, memory and damage affect memory can brain cells. Brain function tested before and after the 14-day study, scans use Positron Emission Tomography (PET) to measure brain activity. Who the healthy longevity lifestyle plan followed demonstrated a five percent reduction in brain metabolism in the part of the brain related directly to memory, called the dorsal lateral prefrontal cortex. "The finding suggests that the brain works more efficiently for those who had pursued the healthy longevity program and needed use not enough glucose to effectively," said small. In addition, performed by the same brain region compared control participants better in verbal fluency a cognitive function, the controlled. "Research shows that in just 14 days changes can simple lifestyle not only general health help, but also memory and brain improve function,", said small. "Our next step is the single impact each lifestyle approach that helps to develop an optimal combination." The study was the Fran and Ray stark Foundation for for Alzheimer's disease research, the Judith Elgart show on aging financed Fund for research on brain aging and the Parlow Solomon Chair.Co-authors were from UCLA study and Daniel Silverman, m.d, Ph.d., Prabha Siddarth, Ph.d., Linda Ercoli Ph.d, Karen Miller, Ph.d, Helen Lavretsky, m.d., Benjamin Wright, m.d., Susan Bookheimer, Ph.d., Jorge Barrio, Ph.d., and Michael Phelps, Ph.d.The American Journal of Geriatric Psychiatry, published monthly, is the Official Journal of the American Association for Geriatric Psychiatry and can http://www.ajgponline.org/ appliance.the online found American Association for Geriatric Psychiatry (http://www.aagponline.org/) is a national, represents and mission is serving its members and the field of geriatric Psychiatrie.AAGP's to improve the knowledge base and standard of practice in geriatric psychiatry through education and research and support for the mental health needs of older Americans.

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Thursday, October 28, 2010

What to Expect When Using Argireline Posted By : Jenny Angrove

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Over the Counter Lip Enhancers will deliver on promises

Over-the-counter products that lips appear fuller are popular with consumers, but this "cosmeceuticals" the lips improve research at the University of Washington shows from buyers. Are not sold to consumers as lip of enhancers with the promise of fuller lips over the counter up to their claims, cosmetic surgery Center's according to a new study at the UW Medical Center published in the May / June issue of the archives of facial plastic surgery. "Many manufacturers have methods for cosmetic enhancement with the promise of results similar to the proven surgical and non-surgical methods, trying, the public desire for quick and painless parlay," said Dr. Sam most, Assistant Professor of plastic and reconstructive surgery in the UW School of medicine. "In many cases these products are sold, at the cosmetics counter or on the Internet as effectively without scientific study, and consumers should carefully you." Where such a product, most and his co-author, Dr. Samson Lee, showed that no lip enhancement in a small study of female patients was detected. "It is important to note, that these patients were all very motivated to try this product" said most. "While no side effects were detected, only 14 percent said you would use it again." The study found that no statistically significant change in lip was detected size in patients who use the product. The duration of treatment ranged from one to four months. Digital before after photos were used to quantify the lip measurements. There are a number of best practices of the lip augmentation including filler injections and surgery, most said. "In the age of each rising demand for facial enhancements, many such devices or"Cosmeceuticals"can be expected that are sold over the counter" most said. "Facial plastic surgeons are responsible for the effectiveness of such products to determine to unbiased, evidence-based advice to our patients." Further studies as those likely to be needed for such products as you come onto the market, "said most."

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Hyaluronic Acid Serum Offers Moisturizing without the Greasy Feel Posted By : Claudia Phillips

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Wednesday, October 27, 2010

Study suggests, insufficient sleep cellular may exacerbate ageing well in the elderly

Researchers have shown that unfolded protein response, a reaction to stress-induced by sleep deprivation, is affected in the brains of old mice. Interpret the results, insufficient sleep in the elderly misfolding results suggest one already impaired protective protein to that inadequate sleep in older people who experience usually sleep disorders already impaired protective response to protein misfolding could intensify, which happens in aging cells could aggravate. "Protein misfolding and aggregation is linked to many diseases such as Alzheimer's and Parkinson's disease," notes author first Nirinjini Naidoo, PhD, Assistant Professor in the Division of sleep medicine. The study will be published in the June issue of the journal of neuroscience. The unfolded protein response (UPR) is a part of quality control systems for the monitoring of protein synthesis in the endoplasmic reticulum, the cellular compartment where some proteins are made. In this study, researchers found that the UPR week old, sleep deprived mice, was activated in 10 - so that misfolded proteins in the endoplasmic reticulum collected by brain cells in the cortex. However, in two-year-old, sleep deprived mice, the UPR has failed to do his job and the endoplasmic reticulum clogged misfolded proteins. Old mice that were accentuated by sleep deprivation were shown that already have an impaired UPR.

Sleeping in mice is characterized by short periods of inactivity, all day and night.Mice you sleep days.to to deprive mice sleep on average about an hour for every two awake, researchers constantly monitored and gently stroked to disturb the mice with a brush in activities.

3, 6, 9 Or 12 hours sleep deprivation proteins from the mouse untersucht.Von six hours of sleep deprivation brain were young mice showed that the UPR system in place was because protein synthesis was turned off by a chaperone protein called GDP GRP78.In contrast, no BiP/GRP78 in old mice continued were so protein synthesis.

Old less of proteins of that inject abnormal proteins than young mice mice and cell death had more old mice of proteins, disrupt as young mice are fuhren.So multiple processes in old mouse brains of sleep deprivation and the overall result is a more collection of misfolded proteins.

"We could speculate, fault at older people make an additional burden on a stated - protein folding - and reduce system sleep", Naidoo says.

Future studies will examine whether multiplication key the effects of aging delay protective proteins and reduces sleep disorders.

Study co-author are Megan Ferber, Monali study was funded on aging master, Yan Zhu and Allan Pack, all Penn.Die by the National Institute.


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Benefits of DIY Anti-Aging Skin Care Posted By : Stuart Michael

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Delete skin wrinkles and sun spots to kill this new procedure

Previous laser treatment for wrinkles and other textural things like acne scars uses to create significan laser_skin resurfacing t wounded. Today, the new surgical skin resurfacing treatment exists, create amazing results with fewer side effects.

Previous laser treatment for wrinkles and other textural issues such as acne scars to create significant injury, "according to Dr. Jeffrey Orringer, Director of the U-M cosmetic dermatology and Laser Center."

"While results were terrific downtime last laser skin resurfacing technologies for patient was significant, and the risks has been significant." As technology improves, the pendulum methodology swung the other way, less risk, but with less pronounced results.Today new surgical skin resurfacing treatment, with a fractional CO2 laser offer both improved results with much fewer side effects, "according to Orringer."

The carbon laser beam is divided into numerous microscopically thin beams, the skin strike and evaporation Sun damaged or scars website.This causes that the skin to tighten, and during healing, produce collagen - protein responsible for skin texture and appearance.

"The small micro bar evaporate basically small pillars of tissue that last two to three days around back to seal" Orringer says."While this healing time, as the skin back together the lost volume essentially created a firming of the skin. also is these columns of the skin where the beam delivers heat, very reproducible creates a mechanism wound healing, which partially leads to the formation of new collagen in the skin."

In addition to smoothen fine lines and wrinkles, says Orringer patients, take the fractional CO2 laser treatment can expect a more even skin tone, as well as results that last for years, not weeks or months.

"To produce collagen, the molecule that really tried this procedure, the body has a half-life of about 15 years." We would expect that, as far as improving patients based on collagen production, a very long time would take their results ", he says."

The carbon dioxide surgical skin treatment procedure takes 45 to 90 minutes.

A current anaesthesia is cream on the field is applied, treated and admissible for about an hour soaking.

Patients are then tiny injections lidocaine to numb in addition the most sensitive parts of the face.

Make sure wrinkles are removed as close to the eyes as possible are protect patients eye shields the laser on the skin given until line can be applied to the eyelash.

"Patients are treated in two passes.""In the first half deeply on the skin lines, atrophic scars and similar actions work on deep," says Orringer."The second, more superficial pass focuses usually affect more blending skin tones and get rid of sun spots and uneven pigmentation."

While the immediate effects of laser treatment include redness, clear serum swelling and oozing liquid called, initial healing takes place primarily within three to four days.

The serum proteins that help containing the skin to heal, still out on the surface of the skin regularly while few days seep the first as the microscopic holes begin to close.

Orringer says, by the third or fourth day it essentially no wound care requires other than applying a thick moisturizer.

Redness gradually scattered across one or two weeks in most patients.

"" The patients experienced an immediate improvement during the treatment the laser, your skin heating zugeordnet.Die collagen contracts make the skin appear instantly firmer "says Orringer.""However, more the kind of improvement collagen production refers to the several weeks in a few months complete continue to see improvements in your skin after the treatment for the first three or four months werden.Patienten."

"As with any surgery or medical treatment there risks. for fractional CO2 laser treatment says Orringer that are relatively small risks.""Concerns such as infection and scarring and skin discoloration are certainly theoretical possibilities and it is something that patients should discuss with your doctor," he says.

Iterates through fractional CO2 laser treatment for those who are considering, Orringer stressed that you should consider:

The setting in which you intend to undergo the procedure.

Who will carry out the treatment?

What exact is used?

The education level of the team of that is going to do the procedure.

"Regulation of laser use differently to Zustand.Dies is a moderately-invasive procedures in some places legally by non-medical personnel erfolgt.Obwohl treatment very safe, if is carried out by experienced doctors complications can view auftreten.meiner should a doctor with specialized training in laser therapy, patients find," says Orringer


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Hyaluronic Acid Changes What Your Skin Says About You Posted By : Claudia Phillips

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Tuesday, October 26, 2010

Summer skin care tips help you look younger. and live longer

Jump to content

The premier muscle and fitness, nutrition and health portal resource summer skin care tips, help you look younger. and live longer E-mail American Academy of Dermatology (Academy) skin care tips generously waterproof sunscreen with a sun protection factor (SPF) of at least 15 that apply broad-spectrum protection from both ultraviolet A (UVA) and ultraviolet B (UVB) to all exposed skin. Again apply every two hours at, even on cloudy days, and after swimming or sweating. Protective clothing including a long sleeve shirt, pants, a wide brim hat and sunglasses, where possible.Seek shadows, if installed, remember that the Sun's rays are strongest between 10 am and 4 am if your shadow is shorter than you are looking shade.Protect children of sunlight by playing in a shade, use of protective clothing, and apply sunscreen.Use extra caution in the vicinity of water, snow and sand as you reflect the Sun's harmful rays that vitamin D safely through a healthy diet can increase your chance of sunburn.Get, vitamin supplements can contain. Want not sun.Avoid solarium. UV light from the Sun and solarium beds can cause skin cancer and wrinkle. If you want to look like you have been in the Sun, consider a sunless self Brown product sunscreen with IT.Check still your birthday suit on your birthday to use.If you change anything notice see growing or bleeding on the skin, a Dermatologen.Hautkrebs is very treatable if caught early.
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Wrinkle Cream with Snap-8 Is Like Botox But Safer Posted By : Jenny Angrove

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Forgetful? You can be your memory more than just lose

Alzheimers DiseaseA part of your brain with your leak memory, according to a study published in neurology, the scientific journal of the American Academy of Neurology older adults who can your "spirit is" actions.

The study, which saw 120 people in the age of 60, found people who complained about significant memory problems but had nor mass density in their brains, although they were not diagnosed with Alzheimer's disease or mild cognitive impairment (MCI), a transition stage between normal aging had reduced gray normal performance on memory tests and the more serious problems with Alzheimer's disease.

Compared to healthy individuals found the study who had complained about significant memory issues a three percent reduction in gray mass density in an area known for memory important; It was a four percent reduction between individuals diagnosed with MCI.

"Significant memory loss complaints may be a very early stage of the"pre "MCI dementia for some people." "This is important because early detection will be critical because drugs change new disease, in an effort developed are to slow down and ultimately to prevent Alzheimer's disease," said study author Andrew Saykin, PsyD, Professor of Radiology at Dartmouth Medical School in Lebanon, New Hampshire, and a member of the American Academy of Neurology and Psychiatry. While normal aging, MCI and Alzheimer's disease associated with the loss of gray matter in the brain, this is probably the first study, quantitatively examine the severity level of cognitive complaints in older adults and directly assess the relationship to the gray matter loss. Saykin says the results underscore the importance of cognitive complaints in older adults, and suggest that those complaints about serious storage problems should be evaluated and monitored closely in the course of time. Memory complaints, a cardinal feature of MCI, which gives high risk for Alzheimer's disease, are reported in 25 to 50 - percent of the older adult population. The study was supported by the National Institute on Aging, Alzheimer's Association, the Hitchcock Foundation, the IRA DeCamp Foundation, the National Science Foundation, NH hospital and the National Alliance for medical image computing.The American Academy of Neurology, an Association of more than 19,000 neurologists and neuroscience professionals, neurologist dedicated to improving patient care through education and Forschung.Ein is a medical doctor with training in Diagnostics, treatment, and specializes in managing diseases of the brain and nervous system such as Alzheimer's disease, epilepsy, Parkinson's disease, multiple sclerosis and stroke. Visit http://www.aan.com/ for more information about the American Academy of Neurology. Reference: September 12, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

The Alzheimer's disease (AD) is the leading cause of dementia that afflicts 24 million people worldwide a slowly progressive disease of the brain that ist.Alzheimer disease is characterized by impairment of memory and lastly by errors in the reasoning, planning, language and perception. The Alzheimer's disease is not a normal part of aging and is not something inevitably happens later in life.It is rarely before the age of 65 gesehen.Die probability of having Alzheimer's disease increases considerably after the age of 70 and can affect approximately 50% of people in the age of 85.

A transitional period between normal aging and dementia is mild cognitive impairment, according to background information in the article.Previous studies have found an association between mild cognitive impairment and diabetes.Poor blood sugar control during which neuron loss can cause time and diabetes is heart disease and stroke, which can increase the risk of cognitive impairment associated with.

Dementia is a progressive brain dysfunction (in Latin "dementia" means irrationality), which results in a restriction of daily activities and in most cases in the long term leads to the need for the Pflege.Demenz that most can cause many diseases a being of Alzheimer's disease.

The probability with dementia increases with advancing Alter.Demenz occurs mainly in the second half of our lives, often after age 65 Jahren.Die incidence of dementia increases with the increasing age of less than 2% for the 65-69 year olds, 5% for the year 75-79 years old and more than 20% for the year 85-89-jahrigen.Jeder third person suffers of moderate or severe dementia over 90 years alt.Etwa suffer half of affected by dementia in Alzheimer's disease.

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Monday, October 25, 2010

What Is Argireline and What Does It Do? Posted By : Jenny Angrove

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Component of niacin may point the way to the anti-aging drugs

In recent years scientists have discovered that a family of enzymes Sirtuins called life in organisms as diverse as yeast, worms and fly dramatically expand can. A number of scientific groups and biotechnology companies are eagerly looking for capable, Sirtuin activity, increase drug candidates in the hope to develop a "anti-ageing" drug. Now, a new study on a different strategy for enabling Sirtuins to unleash your anti-aging powers shows. Naturally occurring substances have shown, Sirtuins, enable resveratrol - including part of red wine called a clinically effective dose, derive although a person would need about two cases of wine per day of resveratrol to drink. Nevertheless the findings have attracted a number of scientific groups and biotechnology companies, of all drug candidates boost now eagerly seeking activity able Sirtuin. The public health benefits that such a "anti-ageing" would drug significant - be as economic returns. Now, shows a new study by scientists at the Wistar Institute on a different strategy for enabling Sirtuins to unleash your anti-aging powers. A report on research the February 9 Edition displays of molecular cell and a podcast interview with the study senior author, Ronen marble stone, Ph.d, Professor in gene expression and regulation program at Wistar, are available at the same time on the Institute Web site (www.wistar.org). Use the techniques of structural biology, demonstrates the Wistar team a component of the common vitamin B3, also known as niacin to a specific Web site on the Sirtuin molecule binds to inhibit their activities. This observation suggests that drugs to prevent the component could vitamin B3, NICOTINAMIDE, from binding to this site the effect of enabling Sirtuins. Any such medication would essentially inhibit the inhibitory effect of NICOTINAMIDE. As in mathematics, the two negative would create a positive - activation of the Sirtuins. "Our results a new avenue for design Sirtuin activation drugs, beat", says marble stone. "The jury is still out whether a drug of this type could result in longer life in humans, but I'm also excited by the way, helping such interventions could prevent age-related health problems such as obesity and type II diabetes." The NICOTINAMIDE binding site can be an especially attractive drug target for other reasons according to marble. His group hopes now, rational drug design techniques to create such a drug use. "Many medicines adverse effects have, because in addition to the intended target, the drugs other biologically active molecules hit, not want to affect you," he says. "This NICOTINAMIDE binding site that we have identified seems clearly to the Sirtuins, so if capable of designing a molecule to you as a target, it should be we very specific for these Sirtuin molecules." Also links to a number of observations about calorie diets and longevity long marble's research on Sirtuins. "People have known for some time that low-calorie diet score in life extension in many organisms, but you did not know why," he says. "Recent research has shown that the connection works at least in part by these Sirtuin molecules." The lead author on the molecular cell study is Brandi D. Sanders at the Wistar Institute. Kehao Zhao, Ph.d, formerly at Wistar and now Novartis Institutes for Biomedical Research Inc. in Cambridge, Massachusetts, a coauthor as James t. Slama is Ph.d, with the College of Pharmacy at the University of Toledo, Ohio. Medium to support the research enhancement program research was universal of the national institutes of health and the Commonwealth of the Pennsylvania Department of health provided. The Wistar Institute is an international leader in biomedical research, with particular expertise in cancer research and vaccine development. Founded in 1892 as the first independent non-profit Biomedical Research Institute in the country, Wistar has kept long renowned Cancer Center called of the National Cancer Institute. Discoveries at Wistar the rubella vaccine have led to the creation, the disease in the United States, rabies vaccines, around the world, and a new rotavirus vaccine exterminated approved in 2006. Wistar researchers have identified many cancer genes and monoclonal antibodies and other important research tools developed. Today Wistar researchers home of eminent melanoma and pioneering scientists working on experimental vaccines against influenza, HIV and other diseases. The Institute actively its invention to the commercial sector to ensure that progress from the lab to the clinic as soon as possible move research transfer. The Wistar Institute: today's discoveries - tomorrow's cures. On the Web at http://www.wistar.org/.

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Sunday, October 24, 2010

Is Hyaluronic Acid Serum Worth the Cost? Posted By : Claudia Phillips

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Recent advances make more effective and easier to use more sunscreen

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With spring in the air, most of us will be arming ourselves with all the essentials that warm weather brings ? flip flops, shorts, sunglasses, sun hats and, of course, sunscreen. The available options in sunscreen protection have become more plentiful than ever, including formulations offering a smoother application or enhanced protection from ultraviolet (UV) light. Fortunately, dermatologists can help you sort through the sunscreen clutter ? separating marketing hype from proven science.

Dermatologist Zoe D. Draelos, MD, FAAD, from High Point, N.C., recently discussed the advances that are making sunscreens more effective and more cosmetically acceptable, including higher Sun Protection Factors (SPFs), UVA protection, smaller particles of active ingredients, and enhanced stability during sun exposure. In addition, she addressed new sunscreen ingredients not yet approved by the U.S. Food and Drug Administration (FDA) that she hopes will provide consumers with broader UV protection in the future. Yet, Dr. Draelos also indicated the need for caution in the use of combination insect repellent and sunscreen products as the warm weather approaches.

“Sunscreens have really evolved over the years, as we now have a variety of formulations ? from creams and gels to lotions and sprays ? that more effectively protect the skin from the sun’s harmful UVA and UVB rays,” said Dr. Draelos. “In the past, a common complaint was that sunscreens felt too sticky or gritty when applied and therefore people avoided applying or reapplying them. But now, more refined formulations have been developed that make sunscreens smoother to the touch and less greasy ? making them easier to wear by themselves or under makeup.”

The SPF number on sunscreens largely reflects the product’s ability to screen out UVB rays, the sun’s shorter wavelength UV rays that are primarily linked to sunburn and skin cancer. In August 2007, the FDA proposed to increase the maximum SPF ratings for sunscreens and categorize the SPF factor, from the lowest to highest protection, to help guide consumers with this selection. Importantly, the FDA also acknowledged that sunscreens should reflect their ability to provide protection from UVA rays. UVA rays are longer UV wavelengths that can pass through window glass and penetrate deeper into the skin. These rays are primarily linked to premature aging and wrinkling of the skin, but the latest scientific evidence indicates that they may also contribute to the development of skin cancer. While the FDA’s 2007 Proposed Sunscreen Monograph has not been finalized, dermatologists are hopeful that the new SPF and UVA protection rating systems will be developed for sunscreens under the new regulations.

So what are consumers to do while awaiting implementation of the FDA’s final rule? While the broad range of currently available SPFs can be confusing, Dr. Draelos explained that higher SPFs do offer incremental protection from the sun’s UV rays.

“It’s important to note that an SPF of 50 doesn’t offer twice the UV protection of an SPF of 25, but a higher SPF can be beneficial for people with very fair complexions or in instances where a person is going on vacation to a very tropical or sun-intense climate,” stated Dr. Draelos. Dr. Draelos also indicated that the American Academy of Dermatology (Academy) recommends a minimum of SPF15 regardless of skin type, and also commented on the importance of selecting a sunscreen that offers UVA protection as well. “Without the FDA’s UVA rating system, this selection is more difficult, but consumers should look for products that indicate ‘broad-spectrum’ on the label or read the active ingredients listed on the back panel." Dr. Draelos noted that a list of active ingredients to look for in broad-spectrum sunscreen can be found on the Academy’s Sunscreen Fact Sheet.

“Sunscreen, which is applied as a coating on top of the skin, has filters which absorb or scatter the UV rays,” said Dr. Draelos. While two of the main active inorganic (physical) filters in sunscreen ? zinc oxide and titanium dioxide ? are very effective in protecting the skin against UV radiation, their gritty consistency can leave a visible white film on the skin. Now, new grinding technologies, known as micronizing, can turn zinc oxide and titanium dioxide into extremely small particles that are more transparent on the surface of the skin. This grinding process allows more microfine zinc oxide or micronized titanium dioxide to be added into sunscreens, increasing the evenness of application to the skin and enhancing UV protection while making the product more cosmetically acceptable.

Another important area of sunscreen improvement is the development of formulations that are more photostable. As Dr. Draelos explained, active ingredients in sunscreen absorb or scatter UV radiation. But in doing so the sunscreen breaks down and becomes less effective, essentially decreasing its SPF and level of UV protection. This is one of the reasons that sunscreen needs to be reapplied frequently. In photostabilized sunscreen, a chemical is added to the formulation to absorb more UV radiation ? allowing the sunscreen molecule to remain unaltered and absorb or scatter UV rays for a longer period of time.

“Photostable sunscreen can be compared to playing a game of hot potato, where once the UV energy strikes the skin, the UV filters in the sunscreen want to get rid of it right away in order to remain effective by transferring it to another UV filter or other added ingredient,” said Dr. Draelos. “For example, the ingredient avobenzone used in many broad-spectrum sunscreens is very unstable when exposed to UV radiation. So, ingredients such as ecamsule, octocrylene, and oxybenzone can be added to make avobenzone more stable, provide better protection, and last longer on the skin.”

Combination products containing both insect repellent and sunscreen have become increasingly popular in recent years. Dr. Draelos explained that while these products offer the convenience of a single application, some scientific evidence indicates that the combination may actually decrease the SPF, and therefore the effectiveness, of the sunscreen component of the product.

In addition, Dr. Draelos noted that there are issues with the application of these products to achieve optimal protection against both biting insects and UV rays. “Although sunscreens should be applied liberally at least every two hours, many insect repellents should only be applied every six hours, and sparingly to exposed skin,” said Dr. Draelos. “Applying a combination product too frequently may pose the risk of insect repellent toxicity, but too few applications may cause photodamage from the lack of UV protection.” Dr. Draelos indicated that although there are many insect repellent-sunscreen products on the market, further research is needed on the efficacy and safety of these combined products, and noted that the FDA is currently considering the development of a regulatory position.

Dr. Draelos added that other UV filters are currently being considered by the FDA as new active ingredients. “The FDA regulates sunscreens as over-the-counter drugs, establishing the conditions under which these products are recognized as safe and effective. If these new active ingredients are approved, they should offer broader UV protection and provide an opportunity for superior formulations in future sunscreens. The availability of additional UV agents means you can do a better job protecting your skin against damaging UV rays.”

Dr. Draelos concluded by reminding that, in addition to wearing sunscreen, the Academy recommends that everyone Be Sun SmartSM by:

Generously applying water-resistant sunscreen with a Sun Protection Factor (SPF) of at least 15 that provides broad-spectrum protection from both ultraviolet A (UVA) and ultraviolet B (UVB) rays to all exposed skin. Re-apply every two hours, even on cloudy days, and after swimming or sweating. Look for the AAD SEAL OF RECOGNITIONTM on products that meet these criteria.Wearing protective clothing, such as a long-sleeved shirt, pants, a wide-brimmed hat and sunglasses, where possible.Seeking shade when appropriate, remembering that the sun’s rays are strongest between 10 a.m. and 4 p.m. If your shadow is shorter than you are, seek shade.Protecting children from sun exposure by playing in the shade, using protective clothing, and applying sunscreen.Using extra caution near water, snow and sand as they reflect the damaging rays of the sun which can increase your chance of sunburn.Getting vitamin D safely through a healthy diet that may include vitamin supplements. Don’t seek the sun.Avoiding tanning beds. Ultraviolet light from the sun and tanning beds can cause skin cancer and wrinkling. If you want to look like you’ve been in the sun, consider using a sunless self-tanning product, but continue to use sunscreen with it.Checking your birthday suit on your birthday. If you notice anything changing, growing, or bleeding on your skin, see a dermatologist. Skin cancer is very treatable when caught early.

Monday, May 5, is Melanoma MondayR and the official launch of Melanoma/Skin Cancer Detection and Prevention MonthR. Through the Academy’s National Melanoma/Skin Cancer Screening Program, dermatologists volunteer to provide free skin cancer screenings in their communities. The public can visit the Academy’s Web site (http://www.aad.org) to find a free skin cancer screening in their area.

For more information about skin cancer, please visit the SkinCancerNet section on www.skincarephysicians.com, a Web site developed by dermatologists that provides patients with up-to-date information on the treatment and management of disorders of the skin, hair and nails.

Headquartered in Schaumburg, Ill., the American Academy of Dermatology (Academy), founded in 1938, is the largest, most influential, and most representative of all dermatologic associations. With a membership of more than 15,000 physicians worldwide, the Academy is committed to: advancing the diagnosis and medical, surgical and cosmetic treatment of the skin, hair and nails; advocating high standards in clinical practice, education, and research in dermatology; and supporting and enhancing patient care for a lifetime of healthier skin, hair and nails. For more information, contact the Academy at 1-888-462-DERM (3376) or http://www.aad.org.

Editor’s Note: A list of broad-spectrum sunscreen ingredients can be found on the Academy’s Sunscreen Fact Sheet at http://www.aad.org/media/background/factsheets/fact_sunscreen.htm.


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What Low Molecular Weight Means for Hyaluronic Acid Posted By : Claudia Phillips

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Wednesday, October 20, 2010